Endocrine Abstracts

Insulinoma is generally a rare benign tumor of the pancreas islet cell. The typical clinical symptom of insulinoma are repetitive hypoglycemia attacks. Insulinoma with coexisting diabetes is extremely rare condition, We aim to present a case with insulinoma conmomittant with type 2 diabetes mellitus.Case report: A 65-year-old woman diagnosed with type 2 diabetes mellitus was admitted by our internal medicine clinic. She complained from perspiration and t...

Aim: Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are prognostic markers of differentiated thyroid cancers. In our study we evaluated NLR, PLR and C-reactive protein for predicting the occurence of differentiated thyroid cancer. This is the first study that compares NLR and PLR to C-reactive protein indifferantiated thyroid cancer not only papillary cancer but also folliculer cancer.Materials and Method: This study includes 51 pa...

Introduction: The purpose of this study was to evaluate the relation between menopausal women and the thiol/disulphide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.Methods: Fourty five postmenopausal subject and 39 healthy participant were included in the study.Results: We found that in postmenopausal group, disulphide (P=0.04), disulphide/native thiol (P=0.004)...

Introduction: The effects of sex steroids on lymphocytes count and functions are well known and it is propounded that autoimmune diseases more common in women. NLO index is an indicator of inflammative situation. In this study, it has been aimed that neutrophil/lymphocytes ratio (NLO) calculation by determining neutrophil/lymphocytes values in patients who diagnosed as hypogonadotropic hypogodanism and searching that whether there is significant difference between healthy grou...

Introduction: Neutrophil lymphocyte rate (NLO), which is obtained from peripheric blood and used as mathematical rates of lymphocyte numbers, is accepted as available and practical indicator of systemic inflammation existence. We aimed to search NLO between Hashimoto’s thyroids patients who have autoimmune thyroid and also include an aetiopathogenesis auto-inflammatory process, and healthy control group with this study.Method: 59 patients who have b...

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

Aim: The risk of cardiovascular mortality is high in patients with acromegaly. In this study, we intent to evaluate serum lipid profile in patients newly diagnosed with acromegaly and determine its association with increased growth hormone (gh) and insulin like growth factor-1 (igf-1) levels.Material and method: This study includes 57 patients newly diagnosed with acromegaly in our hospital (mean age 44.1±13.8 years; mean bmi 29.6±5.4 kg/m...